{"id":7281,"date":"2016-06-01T12:21:12","date_gmt":"2016-06-01T10:21:12","guid":{"rendered":"https:\/\/www.gruptlpbarcelona.org\/research\/"},"modified":"2026-03-09T12:36:19","modified_gmt":"2026-03-09T11:36:19","slug":"research","status":"publish","type":"page","link":"https:\/\/www.gruptlpbarcelona.org\/en\/research\/","title":{"rendered":"Research"},"content":{"rendered":"
<\/span><\/a><\/div><\/div>\"Grup-TLP<\/div>
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Research,
\none of the founding purposes
\nof the Grup TLP Barcelona<\/span><\/span><\/h1><\/div><\/div><\/div><\/div><\/section>

Borderline Personality Disorder (BPD) is not a new condition, but there are still significant gaps in knowledge regarding its possible causes, its identification and diagnosis, and the effectiveness of different treatment options. For this reason, our group has developed strategic research lines on BPD across the lifespan since its inception. <\/p>\n

National and international competitive projects, both single-center and collaborative, as well as independent research initiatives, have been carried out. Their results have been presented at scientific meetings and published in specialized journals.<\/p>\n<\/div><\/div><\/div><\/div>

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With the primary objective of clarifying the diagnosis of the disorder, the different research activities can essentially be summarized in the following lines of investigation:<\/p>\n<\/div><\/div>

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Development and validation, within our context, of instruments for the detection and assessment of BPD.<\/h4><\/div><\/div>
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Study of the potential risk factors that may contribute to the development of the disorder.<\/h4><\/div><\/div>
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Therapeutic approaches for the management of BPD across the lifespan.<\/h4><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section>
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PROJECTS<\/span><\/span><\/h3>
<\/div>\"Grup-TLP<\/div><\/div>
Study of the effectiveness of Transference-Focused Psychotherapy group therapy (TFP-G) in a sample of patients diagnosed with Borderline Personality Disorder.<\/span><\/span><\/div>
Vall d\u2019Hebron Institut de Recerca (VHIR). PR(AG)23\/2024 <\/span><\/span><\/div>

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<\/div>\"Grup-TLP<\/div><\/div>
Study of the effectiveness of Transference-Focused Psychotherapy (TFP) versus Treatment As Usual (TAU) in a sample of patients diagnosed with Borderline Personality Disorder.<\/span><\/span><\/div>
Vall d\u2019Hebron Institut de Recerca (VHIR). PR(AG)503\/2020 <\/span><\/span><\/div>

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+ info<\/span><\/a><\/div><\/div><\/div><\/div>
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Follow-up study of Borderline Personality Disorder: Clinical and neuroimaging reassessment six years after diagnosis in adolescence.<\/span><\/span><\/div>
Fondo de Investigaci\u00f3n Sanitaria. Instituto de Salud Carlos III. PI22\/01131 <\/span><\/span><\/div>

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Early Psychotherapeutic Intervention for Non-Suicidal Self-Injurious Behaviors in Adolescents and Young Adults (Transitional Age Youth; TAY): The Tay_SH Program.<\/span><\/span><\/div>
Vall d\u2019Hebron Institut de Recerca (VHIR). PR(AG)540\/2019 <\/span><\/span><\/div>

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PUBLICATIONS<\/span><\/span><\/h3>
<\/div>\"Grup-TLP<\/div><\/div><\/div><\/div>
The effectiveness of the TaySH (Transitional Age Youth Self-Harm) Program in the management of Non-Suicidal Self-Harm (NSSI) in outpatient adolescents and young adults: A non-randomized controlled pilot study.<\/span><\/span><\/div>
The European Journal of Psychiatry. Volume 39, Issue 2, 2025, 100288 <\/span><\/span><\/div>

Natalia Calvo<\/a>, Silvia Amoretti, Jorge Lugo-Mar\u00edn, Montserrat Oriol, Citlall\u00ed Perez, Josep Antoni Ramos-Quiroga<\/a>, Marc Ferrer<\/a><\/p>\n<\/div><\/div>

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Non-suicidal self-injurious behaviors (NSSI) have become one of the most serious mental health problems among adolescents and young adults worldwide, especially within clinical populations. The main objective of this non-randomized pilot study is to demonstrate the effectiveness of the TaySH Program in a clinical sample of 37 outpatient patients aged between 14 and 25 years (M = 16.70, SD = 1.51), within the developmental stage known as TAY (Transitional Age Youth). <\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/article>\n<\/div>\n<\/div><\/div>

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Childhood maltreatment and non-suicidal self-injury in adolescent population: A systematic review and meta-analysis<\/span><\/span><\/div>
Child Abuse Negl. 2024 Nov;157:107048. <\/span><\/span><\/div>

Natalia Calvo<\/a>, Jorge Lugo-Mar\u00edn, Monterrat Oriol, Citlalli P\u00e9rez-Galbarro, Dami\u00e0 Restoy, Josep Antoni Ramos-Quiroga<\/a>, Marc Ferrer<\/a><\/p>\n<\/div><\/div>

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Non-suicidal self-injury (NSSI) is highly prevalent among adolescents. However, knowledge about the potential factors that may precede and influence its development remains limited. Our objective is to examine the impact of adverse childhood events and, more specifically, the different types of child maltreatment (CM) in adolescents with NSSI. This involves conducting a systematic review and a meta-analysis of the different subtypes of CM (physical and emotional neglect, physical and emotional abuse, sexual abuse) in both clinical and non-clinical samples of adolescents with NSSI. <\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

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<\/div>\"Grup-TLP<\/div><\/div><\/div><\/div>
Efficacy of a synbiotic in the management of adults with Attention-Deficit and Hyperactivity Disorder and\/or Borderline Personality Disorder and high levels of irritability: Results from a multicenter, randomized, placebo-controlled, "basket" trial<\/span><\/span><\/div>
Brain Behav Immun. 2024 Aug;120:360-371. <\/span><\/span><\/div>

Gara Arteaga-Henr\u00edquez, Carolina Ramos-Sayalero, Pol Iba\u00f1ez-Jimenez, Silvia Karina Rosales-Ortiz, T\u00fcnde Kilencz, Carmen Schiweck, Isabel Schnorr, Anne Siegl, Alejandro Arias-Vasquez, Istv\u00e1n Bitter, Christian Fadeuilhe, Marc Ferrer<\/strong>,<\/a> Catharina Lavebratt, Silke Matura, Andreas Reif, J\u00e1nos M R\u00e9thelyi, Vanesa Richarte, Nanda Rommelse, Josep Antoni Ramos-Quiroga<\/strong><\/a><\/p>\n<\/div><\/div>

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Irritability worsens the prognosis of ADHD and BPD, yet therapeutic options remain limited. This randomized, double-blind trial evaluated the efficacy of a synbiotic compared with placebo in adults with ADHD or BPD and high levels of irritability over a 10-week period. The results showed a significantly higher response rate in the group treated with the synbiotic, along with improvements in emotional dysregulation, attentional symptoms, functioning, and perceived stress. The treatment was well tolerated. These findings suggest that the synbiotic could be a complementary option to reduce irritability in a subgroup of patients, although larger studies are needed to confirm this. <\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/article>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/article>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/article>\n<\/div>\n<\/div><\/div>

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<\/div>\"Grup-TLP<\/div><\/div><\/div><\/div>
Brain Functional Correlates of Recall of Life Events in Medication-Na\u00efve Adolescents with Borderline Personality Disorder<\/span><\/span><\/div>
Neuropsychobiology. 2024;83(1):49-60. <\/span><\/span><\/div>

Pilar Salgado Pineda, Marc Ferrer, Natalia Calvo<\/strong><\/a>, Xavier Costa, Mar\u00eda \u00c1ngeles Pozuelo L\u00f3pez, Josep Antoni Ramos-Quiroga, Brenda Tarragona<\/strong>,<\/a> Paola Fuentes-Claramonte, Raymond Salvador, Edith Pomarol-Clotet<\/p>\n<\/div><\/div>

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It has been observed that the recall of autobiographical events is impaired in borderline personality disorder (BPD), but few studies have examined whether this impairment has functional brain correlates. This study evaluated functional brain alterations during autobiographical recall in adolescent patients with no prior treatment in order to avoid potential confounding effects of treatment. Thirty-two adolescent patients with BPD, with no medication and no psychiatric comorbidity, and 33 matched healthy females underwent functional magnetic resonance imaging while viewing individualized cue words that evoked autobiographical memories. Control conditions included the viewing of non-memory-evoking cues and a low-level baseline condition (cross fixation). <\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/article>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/article>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/article>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/article>\n<\/div>\n<\/div><\/div>

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<\/div>\"Grup-TLP<\/div><\/div><\/div><\/div>
Discrimination of Borderline Personality Disorder (BPD) and Attention-Deficit\/Hyperactivity Disorder (ADHD) in adolescents: Spanish version of the Borderline Personality Features Scale for Children-11 Self-Report (BPFSC-11) Preliminary results <\/span><\/span><\/div>
Borderline Personal Disord Emot Dysregul. 2023 May 16;10(1):15. <\/span><\/span><\/div>

Natalia Calvo<\/strong><\/a>, Jorge Lugo Marin, Raquel Vidal, Carla Sharp, Juan D Duque, Josep-Antoni Ramos-Quiroga, Marc Ferrer<\/strong><\/a><\/p>\n<\/div><\/div>

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Although the diagnosis of borderline personality disorder (BPD) during adolescence has been questioned, numerous recent studies have confirmed its validity. However, some clinical manifestations of BPD may also be identified in adolescents with other disorders, such as attention-deficit\/hyperactivity disorder (ADHD). The aim of the present study is to examine the ability of the Borderline Personality Features Scale for Children-11 (BPFSC-11) to discriminate between adolescents with BPD and ADHD. <\/p>\n

One hundred and forty-five participants were grouped according to their diagnosis: 58 with BPD, 58 with ADHD, and 29 healthy volunteers as a control group. Intergroup differences and the ROC curve were analyzed to assess whether the total BPFSC-11 score and\/or its factors can significantly discriminate between BPD and other groups of adolescents. <\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/article>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/article>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/article>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/article>\n<\/div>\n<\/div><\/div>

Read the article<\/span><\/a><\/div><\/div><\/div><\/div>
<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section>\n","protected":false},"excerpt":{"rendered":"Research, one of the founding purposes of the Grup TLP BarcelonaBorderline Personality Disorder (BPD) is not a new condition, but there are still significant gaps in knowledge regarding its possible causes, its identification and diagnosis, and the effectiveness of different treatment options. For this reason, our group has developed strategic research lines on BPD across...","protected":false},"author":5,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-7281","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.gruptlpbarcelona.org\/en\/wp-json\/wp\/v2\/pages\/7281","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.gruptlpbarcelona.org\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.gruptlpbarcelona.org\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.gruptlpbarcelona.org\/en\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/www.gruptlpbarcelona.org\/en\/wp-json\/wp\/v2\/comments?post=7281"}],"version-history":[{"count":2,"href":"https:\/\/www.gruptlpbarcelona.org\/en\/wp-json\/wp\/v2\/pages\/7281\/revisions"}],"predecessor-version":[{"id":7285,"href":"https:\/\/www.gruptlpbarcelona.org\/en\/wp-json\/wp\/v2\/pages\/7281\/revisions\/7285"}],"wp:attachment":[{"href":"https:\/\/www.gruptlpbarcelona.org\/en\/wp-json\/wp\/v2\/media?parent=7281"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}